A self-supervised feature-standardization-block for cross-domain lung disease classification.

Journal: Methods (San Diego, Calif.)
Published Date:

Abstract

With the advance of deep learning technology, convolutional neural network (CNN) has been wildly used and achieved the state-of-the-art performances in the area of medical image classification. However, most existing medical image classification methods conduct their experiments on only one public dataset. When applying a well-trained model to a different dataset selected from different sources, the model usually shows large performance degradation and needs to be fine-tuned before it can be applied to the new dataset. The goal of this work is trying to solve the cross-domain image classification problem without using data from target domain. In this work, we designed a self-supervised plug-and-play feature-standardization-block (FSB) which consisting of image normalization (INB), contrast enhancement (CEB) and boundary detection blocks (BDB), to extract cross-domain robust feature maps for deep learning framework, and applied the network for chest x-ray-based lung diseases classification. Three classic deep networks, i.e. VGG, Xception and DenseNet and four chest x-ray lung diseases datasets were employed for evaluating the performance. The experimental result showed that when employing feature-standardization-block, all three networks showed better domain adaption performance. The image normalization, contrast enhancement and boundary detection blocks achieved in average 2%, 2% and 5% accuracy improvement, respectively. By combining all three blocks, feature-standardization-block achieved in average 6% accuracy improvement.

Authors

  • Xuechen Li
    School of Mathematics and Statistics, Xuchang University, Xuchang 461000, China.
  • Linlin Shen
  • Zhihui Lai
    College of Computer Science and Software Engineering, Shenzhen University, Shenzhen, 518055, Guangdong, China.
  • Zhongliang Li
    College of Computer Science and Software Engineering, AI Research Centre for Medical Image Analysis and Diagnosis and Marshall Laboratory of Biomedical Engineering, Shenzhen University, Shenzhen, Guangdong, China.
  • Juan Yu
    College of Mathematics and System Sciences, Xinjiang University, Urumqi, 830046 Xinjiang, China.
  • Zuhui Pu
    Department of Endocrinology, Institute of Translational Medicine, Health Science Center, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
  • Lisha Mou
    Department of Endocrinology, Institute of Translational Medicine, Health Science Center, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
  • Min Cao
    Guangzhou Panyu Sanatorium, Guangzhou, Guangdong, China.
  • Heng Kong
    Shenzhen Baoan Center Hosipital, Shenzhen, Guangdong, China.
  • Yingqi Li
    Imaging Department, Shenzhen Bao'an District Songgang People's Hospital, Shenzhen, Guangdong, China.
  • Weicai Dai
    Imaging Department, Fifth People's Hospital of Longgang District, Shenzhen, Guangdong, China.