Neuromagnetic high frequency spikes are a new and noninvasive biomarker for localization of epileptogenic zones.

Journal: Seizure
PMID: 33975080

Abstract

OBJECTIVE: One barrier hindering high frequency brain signals (HFBS, >80 Hz) from wide clinical applications is that the brain generates both pathological and physiological HFBS. This study was to find specific biomarkers for localizing epileptogenic zones (EZs).

Authors

  • Jing Xiang
    MEG Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States. Electronic address: Jing.xiang@cchmc.org.
  • Ellen Maue
    MEG Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
  • Han Tong
    MEG Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States; Neuroscience Graduate Program, University of Cincinnati, Cincinnati, OH, United States.
  • Francesco T Mangano
    Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
  • Hansel Greiner
    Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
  • Jeffrey Tenney
    MEG Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.

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