Automated Explainable Multidimensional Deep Learning Platform of Retinal Images for Retinopathy of Prematurity Screening.

Journal: JAMA network open
PMID:

Abstract

IMPORTANCE: A retinopathy of prematurity (ROP) diagnosis currently relies on indirect ophthalmoscopy assessed by experienced ophthalmologists. A deep learning algorithm based on retinal images may facilitate early detection and timely treatment of ROP to improve visual outcomes.

Authors

  • Ji Wang
    Department of Toxicology and Hygienic Chemistry, School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, China.
  • Jie Ji
    Network and Information Center, Shantou University, Shantou, Guangdong, China.
  • Mingzhi Zhang
    Joint Shantou International Eye Center, Shantou University & the Chinese University of Hong Kong, Shantou, China. Electronic address: zmz@jsiec.org.
  • Jian-Wei Lin
    Joint Shantou International Eye Center of Shantou University, the Chinese University of Hong Kong, Shantou, Guangdong, China.
  • Guihua Zhang
    Joint Shantou International Eye Center of Shantou University, the Chinese University of Hong Kong, Shantou, Guangdong, China.
  • Weifen Gong
    Joint Shantou International Eye Center of Shantou University, the Chinese University of Hong Kong, Shantou, Guangdong, China.
  • Ling-Ping Cen
    Guangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, School of Medical Technology, Guangdong Medical University, Zhanjiang, China. cenlp@hotmail.com.
  • Yamei Lu
    Department of Ophthalmology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, Guangdong, China.
  • Xuelin Huang
    Department of Ophthalmology, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China.
  • Dingguo Huang
    Joint Shantou International Eye Center of Shantou University, the Chinese University of Hong Kong, Shantou, Guangdong, China.
  • Taiping Li
    Joint Shantou International Eye Center of Shantou University, the Chinese University of Hong Kong, Shantou, Guangdong, China.
  • Tsz Kin Ng
    Joint Shantou International Eye Center of Shantou University, the Chinese University of Hong Kong, Shantou, Guangdong, China.
  • Chi Pui Pang
    Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong.