Assessing the utility of deep neural networks in predicting postoperative surgical complications: a retrospective study.

Journal: The Lancet. Digital health
PMID: 34215564

Abstract

BACKGROUND: Early detection of postoperative complications, including organ failure, is pivotal in the initiation of targeted treatment strategies aimed at attenuating organ damage. In an era of increasing health-care costs and limited financial resources, identifying surgical patients at a high risk of postoperative complications and providing personalised precision medicine-based treatment strategies provides an obvious pathway for reducing patient morbidity and mortality. We aimed to leverage deep learning to create, through training on structured electronic health-care data, a multilabel deep neural network to predict surgical postoperative complications that would outperform available models in surgical risk prediction.

Authors

  • Alexander Bonde
    Department of Organ Surgery and Transplantation, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
  • Kartik M Varadarajan
    Department of Orthopaedic Surgery, Harris Orthopaedics Laboratory, Massachusetts General Hospital, Boston, Massachusetts.
  • Nicholas Bonde
    Department of Orthopedics, Hvidovre Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
  • Anders Troelsen
    Department of Orthopedics, Copenhagen University Hospital, Hvidovre, Denmark.
  • Orhun K Muratoglu
    Department of Orthopaedic Surgery, Harris Orthopaedics Laboratory, Massachusetts General Hospital, Boston, Massachusetts.
  • Henrik Malchau
    Department of Orthopaedic Surgery, Harris Orthopaedics Laboratory, Massachusetts General Hospital, Boston, MA, USA; Department of Orthopaedic Surgery, Sahlgrenska University Hospital, Sweden.
  • Anthony D Yang
    Surgical Outcomes and Quality Improvement Center (SOQIC), Department of Surgery, Indiana School of Medicine, Indianapolis, IN; Department of Surgery, Division of Surgical Oncology, Indiana University School of Medicine, Indianapolis, IN.
  • Hasan Alam
    Department of Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
  • Martin Sillesen
    Department of Organ Surgery and Transplantation, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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