Multimodal deep learning with feature level fusion for identification of choroidal neovascularization activity in age-related macular degeneration.

Journal: Acta ophthalmologica
PMID:

Abstract

PURPOSE: This study aimed to determine the efficacy of a multimodal deep learning (DL) model using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) images for the assessment of choroidal neovascularization (CNV) in neovascular age-related macular degeneration (AMD).

Authors

  • Kai Jin
    Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Yan Yan
    Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA.
  • Menglu Chen
    Department of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
  • Jun Wang
    Department of Speech, Language, and Hearing Sciences and the Department of Neurology, The University of Texas at Austin, Austin, TX 78712, USA.
  • Xiangji Pan
    Department of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, College of Medicine, Hangzhou, 310009, China.
  • Xindi Liu
    Department of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
  • Mushui Liu
    College of Computer Science and Technology, Zhejiang University, Hangzhou, China.
  • Lixia Lou
    Department of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
  • Yao Wang
    Department of Gastrointestinal Surgery, Zhongshan People's Hospital, Zhongshan, Guangdong, China.
  • Juan Ye
    Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.