Automated detection of cervical ossification of the posterior longitudinal ligament in plain lateral radiographs of the cervical spine using a convolutional neural network.

Journal: Scientific reports
Published Date:

Abstract

Cervical ossification of the posterior longitudinal ligament (OPLL) is a contributing factor to spinal cord injury or trauma-induced myelopathy in the elderly. To reduce the incidence of these traumas, it is essential to diagnose OPLL at an early stage and to educate patients how to prevent falls. We thus evaluated the ability of our convolutional neural network (CNN) to differentially diagnose cervical spondylosis and cervical OPLL. We enrolled 250 patients with cervical spondylosis, 250 patients with cervical OPLL, and 180 radiographically normal controls. We evaluated the ability of our CNN model to distinguish cervical spondylosis, cervical OPLL, and controls, and the diagnostic accuracy was compared to that of 5 board-certified spine surgeons. The accuracy, average recall, precision, and F1 score of the CNN for classification of lateral cervical spine radiographs were 0.86, 0.86, 0.87, and 0.87, respectively. The accuracy was higher for CNN compared to any expert spine surgeon, and was statistically equal to 4 of the 5 experts and significantly higher than that of 1 expert. We demonstrated that the performance of the CNN was equal or superior to that of spine surgeons.

Authors

  • Masataka Miura
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Japan.
  • Satoshi Maki
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Japan; Center for Frontier Medical Engineering, Chiba University, Japan. Electronic address: satoshimaki@gmail.com.
  • Kousei Miura
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
  • Hiroshi Takahashi
    Department of Respiratory Medicine, Saka General Hospital, Sendai, Japan.
  • Masayuki Miyagi
    Department of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
  • Gen Inoue
    Department of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
  • Kazuma Murata
    Department of Orthopedic Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan. kaz.mur26@gmail.com.
  • Takamitsu Konishi
    Department of Orthopedic Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
  • Takeo Furuya
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba, Japan.
  • Masao Koda
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
  • Masashi Takaso
    Department of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
  • Kenji Endo
    Department of Orthopedic Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
  • Seiji Ohtori
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba, Japan.
  • Masashi Yamazaki
    Department of Orthopaedic Surgery, University of Tsukuba (Tsukuba Pediatric Orthopaedic Group), Tsukuba, Japan.