Early balance impairment in Parkinson's Disease: Evidence from Robot-assisted axial rotations.

Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
PMID: 34454269

Abstract

OBJECTIVE: Early postural instability (PI) is a red flag for the diagnosis of Parkinson's disease (PD). Several patients, however, fall within the first three years of disease, particularly when turning. We investigated whether PD patients, without clinically overt PI, manifest abnormal reactive postural responses to ecological perturbations resembling turning.

Authors

  • Alessandro Zampogna
    Department of Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.
  • Ilaria Mileti
    Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy.
  • Francesca Martelli
    Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy.
  • Marco Paoloni
    Department of Physical Medicine and Rehabilitation, Sapienza University of Rome, 00161 Rome, Italy.
  • Zaccaria Del Prete
    Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy.
  • Eduardo Palermo
    Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, 00184 Rome, Italy.
  • Antonio Suppa
    Department of Human Neurosciences, Sapienza University of Rome, Italy; IRCCS Neuromed Institute, Pozzilli, IS, Italy.

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