Deep learning methods for screening patients' S-ICD implantation eligibility.

Journal: Artificial intelligence in medicine
Published Date:

Abstract

Subcutaneous Implantable Cardioverter-Defibrillators (S-ICDs) are used for prevention of sudden cardiac death triggered by ventricular arrhythmias. T Wave Over Sensing (TWOS) is an inherent risk with S-ICDs which can lead to inappropriate shocks. A major predictor of TWOS is a high T:R ratio (the ratio between the amplitudes of the T and R waves). Currently, patients' Electrocardiograms (ECGs) are screened over 10 s to measure the T:R ratio to determine the patients' eligibility for S-ICD implantation. Due to temporal variations in the T:R ratio, 10 s is not a long enough window to reliably determine the normal values of a patient's T:R ratio. In this paper, we develop a convolutional neural network (CNN) based model utilising phase space reconstruction matrices to predict T:R ratios from 10-second ECG segments without explicitly locating the R or T waves, thus avoiding the issue of TWOS. This tool can be used to automatically screen patients over a much longer period and provide an in-depth description of the behavior of the T:R ratio over that period. The tool can also enable much more reliable and descriptive screenings to better assess patients' eligibility for S-ICD implantation.

Authors

  • Anthony J Dunn
    University of Southampton, School of Mathematical Sciences, United Kingdom.
  • Mohamed H ElRefai
    University Hospital of Southampton, United Kingdom.
  • Paul R Roberts
    University Hospital of Southampton, United Kingdom.
  • Stefano Coniglio
    University of Southampton, School of Mathematical Sciences, United Kingdom.
  • Benedict M Wiles
    St George's University Hospitals NHS Foundation Trust, United Kingdom.
  • Alain B Zemkoho
    University of Southampton, School of Mathematical Sciences, United Kingdom. Electronic address: a.b.zemkoho@soton.ac.uk.