CAFT: a deep learning-based comprehensive abdominal fat analysis tool for large cohort studies.

Journal: Magma (New York, N.Y.)
PMID:

Abstract

BACKGROUND: There is increasing appreciation of the association of obesity beyond co-morbidities, such as cancers, Type 2 diabetes, hypertension, and stroke to also impact upon the muscle to give rise to sarcopenic obesity. Phenotypic knowledge of obesity is crucial for profiling and management of obesity, as different fat-subcutaneous adipose tissue depots (SAT) and visceral adipose tissue depots (VAT) have various degrees of influence on metabolic syndrome and morbidities. Manual segmentation is time consuming and laborious. Study focuses on the development of a deep learning-based, complete data processing pipeline for MRI-based fat analysis, for large cohort studies which include (1) data augmentation and preprocessing (2) model zoo (3) visualization dashboard, and (4) correction tool, for automated quantification of fat compartments SAT and VAT.

Authors

  • Prakash Kn Bhanu
    Signal and Image Processing Group, Institute of Bioengineering and Bioimaging, 02-02, Helios,11, Biopolis Way, Singapore, 138667, Singapore. bhanu@ibb.a-star.edu.sg.
  • Channarayapatna Srinivas Arvind
    Signal and Image Processing Group, Institute of Bioengineering and Bioimaging, 02-02, Helios,11, Biopolis Way, Singapore, 138667, Singapore.
  • Ling Yun Yeow
    Signal and Image Processing Group, Institute of Bioengineering and Bioimaging, 02-02, Helios,11, Biopolis Way, Singapore, 138667, Singapore.
  • Wen Xiang Chen
    Department of Diagnostic Radiology, Tan Tock Seng Hospital, 11 Jln Tan Tock Seng, Singapore, 308433, Singapore.
  • Wee Shiong Lim
    Department of Geriatric Medicine, Tan Tock Seng Hospital, 11 Jln Tan Tock Seng, Singapore, 308433, Singapore.
  • Cher Heng Tan
    Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore.