Systemic inflammatory response in robot-assisted and laparoscopic surgery for colon cancer (SIRIRALS): study protocol of a randomized controlled trial.

Journal: BMC surgery
Published Date:

Abstract

BACKGROUND: Robot-assisted surgery is being increasingly adopted in treating colorectal cancer, and the transition from laparoscopic surgery to robot-assisted surgery is a trend. The evidence of the benefits of robot-assisted surgery is sparse. However, findings are associated with improved patient-related outcomes and overall morbidity rates compared to laparoscopic surgery. This induction is unclear, considering both surgical modalities are characterized as minimally invasive. This study aims to evaluate the systemic and peritoneal inflammatory stress response induced by robot-assisted surgery compared with laparoscopic surgery for elective colon cancer resections in a prospective, randomized controlled clinical trial.

Authors

  • Pedja Cuk
    Department of Surgery, Hospital of Southern Jutland, Aabenraa, Denmark. pedja.cuk@rsyd.dk.
  • Andreas Kristian Pedersen
    Department of Regional Health Research, Hospital of Southern Jutland, University of Southern Denmark, Odense, Denmark.
  • Kate Lykke Lambertsen
    Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
  • Christian Backer Mogensen
    Department of Regional Health Research, Hospital of Southern Jutland, University of Southern Denmark, Odense, Denmark.
  • Michael Festersen Nielsen
    Department of Surgery, Hospital of Southern Jutland, Aabenraa, Denmark.
  • Per Helligsø
    Department of Surgery, Hospital of Southern Jutland, Aabenraa, Denmark.
  • Ismail Gögenur
  • Mark Bremholm Ellebæk
    Research Unit for Surgery, Surgical Department, Odense University Hospital, Odense, Denmark.