AIMC Topic: Randomized Controlled Trials as Topic
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Clinical and Economic Evaluation of a Real-Time Chest X-Ray Computer-Aided Detection System for Misplaced Endotracheal and Nasogastric Tubes and Pneumothorax in Emergency and Critical Care Settings: Protocol for a Cluster Randomized Controlled Trial.
JMIR research protocols
Aug 20, 2025
BACKGROUND: Advancements in artificial intelligence (AI) have driven substantial breakthroughs in computer-aided detection (CAD) for chest x-ray (CXR) imaging. The National Taiwan University Hospital research team previously developed an AI-based eme...
Effectiveness of generative artificial intelligence-based teaching versus traditional teaching methods in medical education: a meta-analysis of randomized controlled trials.
BMC medical education
Aug 19, 2025
BACKGROUND: Artificial intelligence (AI) has demonstrated remarkable capabilities across diverse medical applications, potentially revolutionizing healthcare delivery systems. This systematic review and meta-analysis investigated the comparative effe...
Developing a Behavioral Phenotyping Layer for Artificial Intelligence-Driven Predictive Analytics in a Digital Resiliency Course: Protocol for a Randomized Controlled Trial.
JMIR research protocols
Aug 6, 2025
BACKGROUND: Digital interventions for mental health are pivotal for addressing barriers such as stigma, cost, and accessibility, particularly for underserved populations. While the effectiveness of digital interventions has been established, poor adh...
Using a large language model (ChatGPT) to assess risk of bias in randomized controlled trials of medical interventions: protocol for a pilot study of interrater agreement with human reviewers.
BMC medical research methodology
Jul 31, 2025
BACKGROUND: Risk of bias (RoB) assessment is an essential part of systematic reviews that requires reading and understanding each eligible trial and RoB tools. RoB assessment is subject to human error and is time-consuming. Machine learning-based too...
Optimizing treatment for depression in primary care using psychotherapy versus antidepressant medication in a low-resource setting: protocol for the OptimizeD randomized controlled trial.
BMC psychiatry
Jul 30, 2025
BACKGROUND: Psychotherapy and antidepressant medications are first-line treatments for depression, and they both have significant treatment effects on average. However, treatment response varies widely across patients, and neither approach is univers...
Theory-based chatbot for promoting colorectal cancer screening in a community setting in Hong Kong: study protocol of a randomised controlled trial.
BMJ open
Jul 10, 2025
BACKGROUND: Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer mortality worldwide. Despite the organised CRC screening programme, the uptake rate of the population-based CRC screening was still low. Thus, ...
Machine learning assisted adjustment boosts efficiency of exact inference in randomized controlled trials.
Scientific reports
Jul 8, 2025
In this work, we proposed a novel inferential procedure assisted by machine learning based adjustment for randomized control trials. The method was developed under the Rosenbaum's framework of exact tests in randomized experiments with covariate adju...
Medical simulation: an essential tool for training, diagnosis, and treatment in the 21st century.
BMC medical education
Jul 7, 2025
BACKGROUND: Medical simulation is a global trend that improves disease interpretation, diagnostic skills, and clinical abilities, transforming them into skills for the practitioner. Simulator classes should be part of continuing medical education, ge...
MoveMentor-examining the effectiveness of a machine learning and app-based digital assistant to increase physical activity in adults: protocol for a randomised controlled trial.
Trials
Jul 1, 2025
BACKGROUND: Physical inactivity is prevalent, leading to a high burden of disease and large healthcare costs. Thus, there is a need for affordable, effective and scalable interventions. However, interventions that are affordable and scalable are bese...
Large Language Model-Assisted Risk-of-Bias Assessment in Randomized Controlled Trials Using the Revised Risk-of-Bias Tool: Usability Study.
Journal of medical Internet research
Jun 24, 2025
BACKGROUND: The revised Risk-of-Bias tool (RoB2) overcomes the limitations of its predecessor but introduces new implementation challenges. Studies demonstrate low interrater reliability and substantial time requirements for RoB2 implementation. Larg...
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