BACKGROUND: The revised Risk-of-Bias tool (RoB2) overcomes the limitations of its predecessor but introduces new implementation challenges. Studies demonstrate low interrater reliability and substantial time requirements for RoB2 implementation. Larg...
INTRODUCTION: Psychosis, characterised by chronic symptoms often emerging in youth, imposes a substantial burden on individuals and healthcare systems. While early detection and intervention can mitigate this burden, there is limited evidence on the ...
BACKGROUND: Stroke-induced upper limb dysfunction requires functional assessment and rehabilitation. The intelligent rehabilitation assessment and virtual reality training system for upper limb motor function in stroke can accurately and objectively ...
BACKGROUND: CDK4/6 inhibitors plus aromatase inhibitors (AI) significantly improve the therapeutic effect of initial treatment for HR + /HER2- advanced breast cancer. However, there is a lack of head-to-head randomized controlled trials involving the...
AIMS: Children in clinical settings are prone to anxiety due to developmental limitations, which hinders treatment progress. This systematic review and meta-analysis aimed to evaluate the efficacy of social robot interventions compared to routine car...
SUMMARYRecent advances in therapeutic probiotics have shown promising results across various health conditions, reflecting a growing understanding of the human microbiome's role in health and disease. However, comprehensive reviews integrating the di...
BACKGROUND: Individuals who are socioeconomically disadvantaged have high smoking rates and face barriers to participating in smoking cessation interventions. Computer-tailored health communication, which is focused on finding the most relevant messa...
BACKGROUND: Randomised controlled trials (RCTs) commonly estimate intention-to-treat (ITT) estimands. However, when nonadherence to assigned treatment occurs, ITT estimands reflect the effect of being offered treatment, rather than adhering to it and...
INTRODUCTION: Membranous nephropathy is an autoimmune kidney disease and the most common cause of nephrotic syndrome in non-diabetic Caucasian adults. Rituximab is now recommended as first-line therapy for membranous nephropathy. However, Kidney Dise...
BACKGROUND: Robotic rehabilitation, which provides a high-intensity, high-frequency therapy to improve neuroplasticity, is gaining traction. However, its effectiveness for upper extremity stroke rehabilitation remains uncertain. This study comprehens...
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