DeepTOFSino: A deep learning model for synthesizing full-dose time-of-flight bin sinograms from their corresponding low-dose sinograms.

Journal: NeuroImage
Published Date:

Abstract

PURPOSE: Reducing the injected activity and/or the scanning time is a desirable goal to minimize radiation exposure and maximize patients' comfort. To achieve this goal, we developed a deep neural network (DNN) model for synthesizing full-dose (FD) time-of-flight (TOF) bin sinograms from their corresponding fast/low-dose (LD) TOF bin sinograms.

Authors

  • Amirhossein Sanaat
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland.
  • Hossein Shooli
    Persian Gulf Nuclear Medicine Research Center, Department of Molecular Imaging and Radionuclide Therapy (MIRT), Bushehr Medical University Hospital, Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
  • Sohrab Ferdowsi
    HES-SO University of Applied Sciences and Arts Western Switzerland, Geneva, Switzerland.
  • Isaac Shiri
    Biomedical and Health Informatics, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Hossein Arabi
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva 4, Switzerland.
  • Habib Zaidi
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva 4, Switzerland. habib.zaidi@hcuge.ch.