Improving Sensitivity of Arterial Spin Labeling Perfusion MRI in Alzheimer's Disease Using Transfer Learning of Deep Learning-Based ASL Denoising.

Journal: Journal of magnetic resonance imaging : JMRI
PMID:

Abstract

BACKGROUND: Arterial spin labeling (ASL) perfusion magnetic resonance imaging (MRI) denoising through deep learning (DL) often faces insufficient training data from patients. One solution is to train DL models using healthy subjects' data which are more widely available and transfer them to patients' data.

Authors

  • Lei Zhang
    Division of Gastroenterology, Union Hospital, Tongji Medical College Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Danfeng Xie
    Department of Electrical and Computer Engineering, Temple University, Philadelphia, PA, USA.
  • Yiran Li
    University of California at Davis, Davis, CA, USA.
  • Aldo Camargo
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Donghui Song
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Tong Lu
    Department of Emergency Medicine, Jining No.1 People's Hospital, Jining, China.
  • Jean Jeudy
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • David Dreizin
    From the Emergency and Trauma Imaging, Department of Diagnostic Radiology and Nuclear Medicine (D.D.), R Adams Cowley Shock Trauma Center, School of Medicine, University of Maryland; Department of Computer Science (Y.Z.), Center for Cognition Vision and Learning, Johns Hopkins University; Diagnostic Radiology and Nuclear Medicine (T.C., G.L.), University of Maryland School of Medicine; Department of Computer Science (A.L.Y.), Center for Cognition Vision and Learning, Johns Hopkins University; Vascular Surgery (A.M., J.J.M.), R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland.
  • Elias R Melhem
    Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Ze Wang
    School of Traditional Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, 312 Anshanwest Road, Nankai District, Tianjin 300193, China.