Fully Automated Gross Tumor Volume Delineation From PET in Head and Neck Cancer Using Deep Learning Algorithms.

Journal: Clinical nuclear medicine
Published Date:

Abstract

PURPOSE: The availability of automated, accurate, and robust gross tumor volume (GTV) segmentation algorithms is critical for the management of head and neck cancer (HNC) patients. In this work, we evaluated 3 state-of-the-art deep learning algorithms combined with 8 different loss functions for PET image segmentation using a comprehensive training set and evaluated its performance on an external validation set of HNC patients.

Authors

  • Isaac Shiri
    Biomedical and Health Informatics, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Hossein Arabi
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva 4, Switzerland.
  • Amirhossein Sanaat
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland.
  • Elnaz Jenabi
    Research Centre for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Minerva Becker
    Division of Radiology, Geneva University Hospital.
  • Habib Zaidi
    Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva 4, Switzerland. habib.zaidi@hcuge.ch.