AIMC Topic: Head and Neck Neoplasms
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Network-based approach identifies key genes associated with tumor heterogeneity in HPV positive and negative head and neck cancer patients.
Scientific reports
Aug 7, 2025
Head and Neck Squamous Cell Carcinoma (HNSCC) is the seventh most prevalent cancer worldwide and is classified as human papillomavirus (HPV) positive or negative. Substantial heterogeneity has been observed in the two groups, posing a significant cli...
A multimodal dataset for precision oncology in head and neck cancer.
Nature communications
Aug 4, 2025
Head and neck cancer is a common disease and is associated with a poor prognosis. A promising approach to improving patient outcomes is personalized treatment, which uses information from a variety of modalities. However, only little progress has bee...
Deep learning-based real-time detection of head and neck tumors during radiation therapy.
Physics in medicine and biology
Jul 31, 2025
Clinical drivers for real-time head and neck (H&N) tumor tracking during radiation therapy (RT) are accounting for motion caused by changes to the immobilization mask fit, and to reduce mask-related patient distress by replacing the masks with patien...
A deep learning model for predicting radiation-induced xerostomia in patients with head and neck cancer based on multi-channel fusion.
BMC medical imaging
Jul 30, 2025
OBJECTIVES: Radiation-induced xerostomia is a common sequela in patients who undergo head and neck radiation therapy. This study aims to develop a three-dimensional deep learning model to predict xerostomia by fusing data from the gross tumor volume ...
Innovative organ-on-a-chip platforms for exploring tumorigenesis and therapy in head and neck cancer.
Journal of translational medicine
Jul 16, 2025
BACKGROUND: Head and neck cancer (HNC) presents significant research challenges due to the complexity of its tumor microenvironment (TME) and the heterogeneity across different cancer subtypes. Recent advancements in three-dimensional (3D) culture mo...
Auto-Segmentation via deep-learning approaches for the assessment of flap volume after reconstructive surgery or radiotherapy in head and neck cancer.
Scientific reports
Jul 1, 2025
Reconstructive flap surgery aims to restore the substance and function losses associated with tumor resection. Automatic flap segmentation could allow quantification of flap volume and correlations with functional outcomes after surgery or post-opera...
Artificial Intelligence for Head and Neck Squamous Cell Carcinoma: From Diagnosis to Treatment.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
Jun 9, 2025
Head and neck squamous cell carcinoma (HNSCC) remains a globally prevalent malignancy with high morbidity and mortality. Despite therapeutic advances, patient outcomes are hindered by tumor heterogeneity, treatment-related toxicity, and the limitatio...
Integrative bioinformatics and machine learning identify key crosstalk genes and immune interactions in head and neck cancer and Hodgkin lymphoma.
Scientific reports
May 6, 2025
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive malignancy with complex molecular underpinnings. Hodgkin lymphoma (HL), another distinct cancer type, shares several biological characteristics with HNSCC, particularly regarding im...
A Novel Natural Language Processing Model for Triaging Head and Neck Patient Appointments.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Apr 25, 2025
OBJECTIVE: Inaccurate patient triage contributes to suboptimal clinical capacity management and delays in patient care, which in cancer patients may significantly increase morbidity and mortality. We developed a natural language processing (NLP) mode...
Reinforcement learning-driven automated head and neck simultaneous integrated boost (SIB) radiation therapy: flexible treatment planning aligned with clinical preferences.
Physics in medicine and biology
Apr 22, 2025
Head-and-neck simultaneous integrated boost (SIB) treatment planning using intensity modulated radiation therapy is particularly challenging due to the proximity to organs-at-risk. Depending on the specific clinical conditions, different parotid-spar...
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