CNN-PepPred: an open-source tool to create convolutional NN models for the discovery of patterns in peptide sets-application to peptide-MHC class II binding prediction.

Journal: Bioinformatics (Oxford, England)
Published Date:

Abstract

SUMMARY: The ability to unveil binding patterns in peptide sets has important applications in several biomedical areas, including the development of vaccines. We present an open-source tool, CNN-PepPred, that uses convolutional neural networks to discover such patterns, along with its application to peptide-HLA class II binding prediction. The tool can be used locally on different operating systems, with CPUs or GPUs, to train, evaluate, apply and visualize models.

Authors

  • Valentin Junet
    Anaxomics Biotech SL, Barcelona 08008, Spain.
  • Xavier Daura
    Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona, Barcelona 08193, Spain.