Automated Assessment of Brain CT After Cardiac Arrest-An Observational Derivation/Validation Cohort Study.

Journal: Critical care medicine
PMID: 34374503

Abstract

OBJECTIVES: Prognostication of outcome is an essential step in defining therapeutic goals after cardiac arrest. Gray-white-matter ratio obtained from brain CT can predict poor outcome. However, manual placement of regions of interest is a potential source of error and interrater variability. Our objective was to assess the performance of poor outcome prediction by automated quantification of changes in brain CTs after cardiac arrest.

Authors

  • Martin Kenda
    Department of Neurology with Experimental Neurology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Michael Scheel
    Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health (BIH), Department of Neurology, 10117 Berlin, Germany; Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health (BIH), NeuroCure Clinical Research Center, 10117 Berlin, Germany; Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universitt zu Berlin, Berlin Institute of Health (BIH), Department of Neuroradiology, 10117 Berlin, Germany.
  • André Kemmling
    Department of Clinical Radiology, University of Münster, Münster, Germany.
  • Noelle Aalberts
    Department of Neurology with Experimental Neurology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Christopher Guettler
    Department of Neuroradiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Kaspar J Streitberger
    Department of Neurology with Experimental Neurology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Christian Storm
    Department of Nephrology and Intensive Care Medicine, Charité-Universitätsmedizin, Berlin, Germany.
  • Christoph J Ploner
    Department of Neurology with Experimental Neurology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Christoph Leithner
    Department of Neurology with Experimental Neurology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

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