Artificial Intelligence Based Study Association between p53 Gene Polymorphism and Endometriosis: A Systematic Review and Meta-analysis.

Journal: Computational intelligence and neuroscience
Published Date:

Abstract

BACKGROUND: The P53 gene is critical to the onset and progression of cancers. Currently, relevant study findings indicate that the p53 gene may have a strong association with the risk of endometriosis, but these findings have not been united. To gather more statistically meaningful clinical data, we used meta-analysis to examine the relationship between the rs1042522 single nucleotide polymorphism of the tumor suppressor gene p53 and the incidence of endometriosis.

Authors

  • Xia Ma
    Department of Pulmonary and Critical Care Medicine, General Hospital of Datong Coal Mine Group Co., Ltd., Datong, 037000, China.
  • Xiaoxiao Jin
    Department of Obstetrics and Gynecology, Taizhou Hospital, Taizhou 317000, Zhejiang, China.
  • Xiujuan Shao
    Department of Obstetrics and Gynecology, Taizhou Hospital, Taizhou 317000, Zhejiang, China.
  • Wanjing Hu
    Department of Obstetrics and Gynecology, Taizhou Women and Children's Hospital, Taizhou 318000, Zhejiang, China.
  • Haihong Jin
    Department of Obstetrics, Taizhou Hospital, Taizhou 317000, Zhejiang, China.
  • Yiqun Wang
    Department of Anesthesiology, Affiliated Nanhua Hospital, University of South China, Hengyang 421002, Hunan Province, China.