AIMC Topic: Endometriosis

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WISP2/CCN5 revealed as a potential diagnostic biomarker for endometriosis based on machine learning and single-cell transcriptomic analysis.

Functional & integrative genomics
OBJECTIVE: Endometriosis is a prevalent gynecological disease characterized by the ectopic growth of functional endometrial tissue outside the uterine cavity, affecting millions of women worldwide. Currently, the definitive diagnosis relies on invasi...

Hybrid Neural network and machine learning models with improved optimization method for gut microbiome effects on the sleep quality in patients with endometriosis.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Endometriosis is a chronic gynecological condition known to affect the quality of life of millions of women globally, often manifesting with symptoms that impact sleep quality. Emerging evidence suggests a crucial role of th...

The inconsistent pathogenesis of endometriosis and adenomyosis: insights from endometrial metabolome and microbiome.

mSystems
UNLABELLED: Endometriosis (EM) and adenomyosis (AM) are interrelated gynecological disorders characterized by the aberrant presence of endometrial tissue and are frequently linked with chronic pelvic pain and infertility, yet their pathogenetic mecha...

Identification and validation of a novel machine learning model for predicting severe pelvic endometriosis: A retrospective study.

Scientific reports
This study aimed to explore potential risk factors for severe endometriosis and to develop a model to predict the risk of severe endometriosis. A total of 308 patients with endometriosis were analyzed. Least absolute shrinkage and selection operator ...

Development and Validation an AI Model to Improve the Diagnosis of Deep Infiltrating Endometriosis for Junior Sonologists.

Ultrasound in medicine & biology
OBJECTIVE: This study aims to develop and validate an artificial intelligence (AI) model based on ultrasound (US) videos and images to improve the performance of junior sonologists in detecting deep infiltrating endometriosis (DE).

Identification of common diagnostic genes and molecular pathways in endometriosis and systemic lupus erythematosus by machine learning approach and in vitro experiment.

International journal of medical sciences
Growing research suggests that endometriosis and systemic lupus erythematosus (SLE) are both chronic inflammatory diseases and closely related, but no studies have explored their common molecular characteristics and underlying mechanisms. Based on GE...

Utilizing AI for the Identification and Validation of Novel Therapeutic Targets and Repurposed Drugs for Endometriosis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Endometriosis affects over 190 million women globally, and effective therapies are urgently needed to address the burden of endometriosis on women's health. Using an artificial intelligence (AI)-driven target discovery platform, two unreported therap...

Application of machine learning techniques in the diagnosis of endometriosis.

BMC women's health
OBJECTIVE: The aim of this study is to assess the use of machine learning methodologies in the diagnosis of endometriosis (EM).

Endometriosis Online Communities: How Machine Learning Can Help Physicians Understand What Patients Are Discussing Online.

Journal of minimally invasive gynecology
STUDY OBJECTIVE: Use machine learning to characterize the content of endometriosis online community posts and comments.

Identification of programmed cell death-related genes and diagnostic biomarkers in endometriosis using a machine learning and Mendelian randomization approach.

Frontiers in endocrinology
BACKGROUND: Endometriosis (EM) is a prevalent gynecological disorder frequently associated with irregular menstruation and infertility. Programmed cell death (PCD) is pivotal in the pathophysiological mechanisms underlying EM. Despite this, the preci...