Deep learning for screening primary osteopenia and osteoporosis using spine radiographs and patient clinical covariates in a Chinese population.

Journal: Frontiers in endocrinology
PMID:

Abstract

PURPOSE: Many high-risk osteopenia and osteoporosis patients remain undiagnosed. We proposed to construct a convolutional neural network model for screening primary osteopenia and osteoporosis based on the lumbar radiographs, and to compare the diagnostic performance of the CNN model adding the clinical covariates with the image model alone.

Authors

  • Liting Mao
    Department of Radiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Ziqiang Xia
    Department of Radiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Liang Pan
    Department of Radiology, Third Affiliated Hospital of Soochow University, Changzhou Jiangsu 213003.
  • Jun Chen
    Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Xian Liu
    Department of Radiology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, PR China.
  • Zhiqiang Li
    The Affiliated Hospital of Qingdao University, The Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes), Qingdao University, Qingdao, 266003, China.
  • Zhaoxian Yan
    Department of Radiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Gengbin Lin
    Department of Radiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Huisen Wen
    Department of Radiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Bo Liu
    Wuhan United Imaging Healthcare Surgical Technology Co., Ltd., Wuhan, China.