AIMC Topic: Osteoporosis

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Exploration of autophagy-associated genes and potential molecular mechanisms in type 1 diabetes and osteoporosis.

Scientific reports Aug 11, 2025
The co-occurrence of osteoporosis (OP) and type 1 diabetes mellitus (T1DM) represents a clinically significant comorbidity pattern, characterized by skeletal fragility and insulin deficiency. While epidemiological links exist, their shared molecular ...
Diabetes Mellitus, Type 1 MicroRNAs Autophagy Gene Expression Regulation Humans Osteoporosis Gene Expression Profiling Gene Regulatory Networks
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Opportunistic computed tomography (CT) assessment of osteoporosis in patients undergoing transcatheter aortic valve replacement (TAVR).

Archives of osteoporosis Jul 17, 2025
UNLABELLED: CT-based opportunistic screening using artificial intelligence finds a high prevalence (43%) of osteoporosis in CT scans obtained for planning of transcatheter aortic valve replacement. Thus, opportunistic screening may be a cost-effectiv...
Aged, 80 and over Male Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Humans Tomography, X-Ray Computed Female Artificial Intelligence Aged Algorithms Bone Density Osteoporosis
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Deep learning algorithm for identifying osteopenia/osteoporosis using cervical radiography.

Scientific reports Jul 12, 2025
Due to symptomatic gait imbalance and a high incidence of falls, patients with cervical disease-including degenerative cervical myelopathy-have a significantly increased risk of fragility fractures. To prevent such fractures in patients with cervical...
Neural Networks, Computer Algorithms Osteoporosis Female Humans Lumbar Vertebrae Bone Diseases, Metabolic Femur Neck Middle Aged Aged Deep Learning Sensitivity and Specificity Radiography Male Cervical Vertebrae
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A novel dual embedding few-shot learning approach for classifying bone loss using orthopantomogram radiographic notes.

Head & face medicine Jul 11, 2025
BACKGROUND: Orthopantomograms (OPGs) are essential diagnostic tools in dental and maxillofacial care, providing a panoramic view of the jaws, teeth, and surrounding bone structures. Detecting bone loss, which indicates periodontal disease and systemi...
Humans Machine Learning Osteoporosis Natural Language Processing Radiography, Panoramic Alveolar Bone Loss
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Radiomics and machine learning for osteoporosis detection using abdominal computed tomography: a retrospective multicenter study.

BMC medical imaging Jul 1, 2025
OBJECTIVE: This study aimed to develop and validate a predictive model to detect osteoporosis using radiomic features and machine learning (ML) approaches from lumbar spine computed tomography (CT) images during an abdominal CT examination.
Radiography, Abdominal Support Vector Machine Radiographic Image Interpretation, Computer-Assisted Lumbar Vertebrae Female Aged Aged, 80 and over Radiomics Male Middle Aged ROC Curve Machine Learning Retrospective Studies Osteoporosis Tomography, X-Ray Computed Humans
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Artificial intelligence for predicting the risk of bone fragility fractures in osteoporosis.

European radiology experimental Jun 24, 2025
Osteoporosis is widespread with a high incidence rate, resulting in fragility fractures which are a major contributor to mortality among the elderly. Artificial intelligence (AI), in particular artificial neural networks, appears to be useful in mana...
Humans Neural Networks, Computer Artificial Intelligence Bone Density Osteoporosis Risk Assessment Osteoporotic Fractures
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Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations.

Current osteoporosis reports May 24, 2025
PURPOSE OF REVIEW: Genome-wide association studies (GWAS) have significantly advanced osteoporosis research by identifying genetic loci associated with bone mineral density (BMD) and fracture risk. However, disparities persist due to the underreprese...
African People Low Density Lipoprotein Receptor-Related Protein-5 Machine Learning Asian People Humans Bone Density White People Genomics Osteoporosis Gene-Environment Interaction Genetic Predisposition to Disease Genome-Wide Association Study Osteoporotic Fractures Core Binding Factor Alpha 1 Subunit
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Resting-State Functional MRI Reveals Altered Seed-Based Connectivity in Diabetic Osteoporosis Patients.

Clinical interventions in aging May 21, 2025
BACKGROUND: Diabetic osteoporosis (DOP) can cause abnormal brain neural activity, but its mechanism is still unclear. This study aims to further explore the abnormal functional connectivity between different brain regions based on the team's previous...
Female Aged Male Middle Aged Humans Diabetes Mellitus, Type 2 Brain Magnetic Resonance Imaging Osteoporosis Osteocalcin
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Accelerated ultrashort echo time quantitative magnetization transfer (UTE-qMT) imaging of macromolecular fraction (MMF) in cortical bone based on a self-attention convolutional neural network.

Magnetic resonance imaging May 4, 2025
PURPOSE: To combine ultrashort echo time quantitative magnetization transfer (UTE-qMT) imaging with a self-attention convolutional neural network (SAT-Net) for accelerated mapping of macromolecular fraction (MMF) in cortical bone.
Middle Aged Magnetic Resonance Imaging Osteoporosis Convolutional Neural Networks Tibia Female Image Processing, Computer-Assisted Bone Diseases, Metabolic Humans Young Adult Cortical Bone Neural Networks, Computer Adult Algorithms
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Deep Learning-enhanced Opportunistic Osteoporosis Screening in Ultralow-Voltage (80 kV) Chest CT: A Preliminary Study.

Academic radiology May 2, 2025
RATIONALE AND OBJECTIVES: To explore the feasibility of deep learning (DL)-enhanced, fully automated bone mineral density (BMD) measurement using the ultralow-voltage 80 kV chest CT scans performed for lung cancer screening.
Female Feasibility Studies Aged Radiography, Thoracic Aged, 80 and over Middle Aged Bone Density Male Deep Learning Retrospective Studies Humans Lung Neoplasms Osteoporosis Radiographic Image Interpretation, Computer-Assisted Tomography, X-Ray Computed
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