Development and validation of a deep learning model for detection of breast cancers in mammography from multi-institutional datasets.

Journal: PloS one
Published Date:

Abstract

OBJECTIVES: The objective of this study was to develop and validate a state-of-the-art, deep learning (DL)-based model for detecting breast cancers on mammography.

Authors

  • Daiju Ueda
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan. ai.labo.ocu@gmail.com.
  • Akira Yamamoto
    From the Department of Diagnostic and Interventional Radiology (D.U., A.Y., T.S., S.D., A.S., Y.M.) and Department of Premier Preventive Medicine (S.F.), Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan; LPixel, Tokyo, Japan (M.N., A.C., Y.S.); and Department of Radiology, Osaka City University Hospital, Osaka, Japan (Y.K.).
  • Naoyoshi Onoda
    Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Tsutomu Takashima
  • Satoru Noda
    Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Shinichiro Kashiwagi
    Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Tamami Morisaki
    Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Shinya Fukumoto
    Department of Premier Preventive Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
  • Masatsugu Shiba
    Department of Gastroenterology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
  • Mina Morimura
    Department of General Practice, Osaka City University Hospital, Osaka, Japan.
  • Taro Shimono
    From the Department of Diagnostic and Interventional Radiology (D.U., A.Y., T.S., S.D., A.S., Y.M.) and Department of Premier Preventive Medicine (S.F.), Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan; LPixel, Tokyo, Japan (M.N., A.C., Y.S.); and Department of Radiology, Osaka City University Hospital, Osaka, Japan (Y.K.).
  • Ken Kageyama
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
  • Hiroyuki Tatekawa
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Kazuki Murai
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
  • Takashi Honjo
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Akitoshi Shimazaki
    From the Department of Diagnostic and Interventional Radiology (D.U., A.Y., T.S., S.D., A.S., Y.M.) and Department of Premier Preventive Medicine (S.F.), Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan; LPixel, Tokyo, Japan (M.N., A.C., Y.S.); and Department of Radiology, Osaka City University Hospital, Osaka, Japan (Y.K.).
  • Daijiro Kabata
    From the Departments of Diagnostic and Interventional Radiology (D.U., A.Y., S.L.W., H. Tatekawa, H. Takita, T.H., A.S., Y.M.), Neurosurgery (T. Ichinose, H.A., Y.W., T.G.), and Medical Statistics (D.K.), Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan; and Department of Radiology, Osaka City University Hospital, 1-5-7 Asahi-machi, Abeno-ku, Osaka, 545-8586, Japan (Y.K., T. Ichida).
  • Yukio Miki
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.