Screening of Potential Biomarkers in the Peripheral Serum for Steroid-Induced Osteonecrosis of the Femoral Head Based on WGCNA and Machine Learning Algorithms.

Journal: Disease markers
PMID:

Abstract

BACKGROUND: Steroid-induced osteonecrosis of the femoral head (SONFH) has produced a substantial burden of medical and social experience. However, the current diagnosis is still limited. Thus, this study is aimed at identifying potential biomarkers in the peripheral serum of patients with SONFH.

Authors

  • Jian Zhang
    College of Pharmacy, Ningxia Medical University, Yinchuan, NingxiaHui Autonomous Region, China.
  • Chi Huang
    Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150001 Heilongjiang, China.
  • Zehan Liu
    Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150001 Heilongjiang, China.
  • Shuai Ren
    Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150001 Heilongjiang, China.
  • Zilong Shen
    Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150001 Heilongjiang, China.
  • Kecheng Han
    Department of Orthopedics, The Fifth Hospital of Harbin, Harbin, 150040 Heilongjiang, China.
  • Weiguang Xin
    Department of Orthopedics, The Second Hospital of Heilongjiang Province, Harbin, 150000 Heilongjiang, China.
  • Guanyi He
    Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150001 Heilongjiang, China.
  • Jianyu Liu
    Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150001 Heilongjiang, China.