Ontology-based identification and prioritization of candidate drugs for epilepsy from literature.
Journal:
Journal of biomedical semantics
Published Date:
Jan 24, 2022
Abstract
BACKGROUND: Drug repurposing can improve the return of investment as it finds new uses for existing drugs. Literature-based analyses exploit factual knowledge on drugs and diseases, e.g. from databases, and combine it with information from scholarly publications. Here we report the use of the Open Discovery Process on scientific literature to identify non-explicit ties between a disease, namely epilepsy, and known drugs, making full use of available epilepsy-specific ontologies.