Formulation and solid state characterization of carboxylic acid-based co-crystals of tinidazole: An approach to enhance solubility.

Journal: Polimery w medycynie
Published Date: Jan 1, 2018

Abstract

BACKGROUND: Tinidazole (TNZ) is an anti-parasite drug used in the treatment of a variety of amebic and parasitic infections. It has low solubility in aqueous media and is categorized under Class II of the Biopharmaceutical Classification System.

Authors

  • Jyotsana R Madan
    Department of Pharmaceutics, Smt. Kashibai Navale College of Pharmacy, Savitribai Phule Pune University, India.
  • Rishikesh H Dagade
    Department of Pharmaceutics, Smt. Kashibai Navale College of Pharmacy, Savitribai Phule Pune University, India.
  • Rajendra Awasthi
    Amity Institute of Pharmacy, Amity University, Noida, India.
  • Kamal Dua
    Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, NSW 2007, Australia.

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