This study investigates the use of simulated data to train deep learning models for denoising infrared spectral images of paraffin-embedded tissue sections in clinical applications. Noise in Fourier-transform infrared spectroscopy poses significant c...
Sjögren's disease is often an underdiagnosed autoimmune condition that primarily affects the exocrine glands, resulting in symptoms such as dry eyes and dry mouth. Diagnostic challenges stem from nonspecific symptoms, the absence of definitive biomar...
Clinica chimica acta; international journal of clinical chemistry
Oct 14, 2025
Chronic Kidney Disease (CKD) is a highly prevalent non-communicable disorder lacking a gold standard method for diagnosis. Early-stage CKD remains undiagnosed and untreated leading to the disease progression. The study aimed to discriminate urine sam...
Ciprofloxacin (CFX) is a potent antibiotic for respiratory infections, but its poor solubility and high crystallinity limit its effectiveness in dry powder inhaler (DPI) delivery. Although soluble forms such as CFX hydrochloride are available, their ...
This study presents rapid, reagent-free detection of COVID-19 using miniaturized MEMS-based Fourier-transform infrared (FTIR) spectrometers integrated with machine learning models. Two portable spectrometers analyze 363 nasopharyngeal swab samples st...
UNLABELLED: is one of the most frequently reported healthcare-associated pathogens. The current gold standard approach to perform the epidemiological typing of these bacteria is Whole Genome Sequencing (WGS), which is an expensive and challenging pr...
Hyperspectral imaging has shown significant applicability in the medical field, particularly for its ability to represent spectral information that can differentiate specific biomolecular characteristics in tissue samples. However, the complexity of ...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Aug 15, 2025
Diabetic encephalopathy is a progressive complication of type 2 diabetes, yet its region-specific biochemical changes remain unclear. In this study, we applied Fourier Transform Infrared Microspectroscopy (FTIRM) to assess metabolic alterations in th...
Journal of pharmaceutical and biomedical analysis
Aug 7, 2025
Curcumae Rhizoma (Ezhu) is a multi-species herbal medicine with excellent medicinal value and development potential. However, challenges such as the difficulty in differentiating its varieties and the limitations of current methods for determining mi...
In this study, we investigate the efficacy of optical photothermal infrared (O-PTIR) spectroscopy, also known as mid-infrared photothermal (MIP) microscopy, for label-free and nondestructive detection of micro- and nanoplastics (MNPs) down to diamete...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.