Artificial intelligence for stepwise diagnosis and monitoring of COVID-19.

Journal: European radiology
Published Date:

Abstract

BACKGROUND: Main challenges for COVID-19 include the lack of a rapid diagnostic test, a suitable tool to monitor and predict a patient's clinical course and an efficient way for data sharing among multicenters. We thus developed a novel artificial intelligence system based on deep learning (DL) and federated learning (FL) for the diagnosis, monitoring, and prediction of a patient's clinical course.

Authors

  • Hengrui Liang
    China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Yuchen Guo
    Institute for Brain and Cognitive Sciences, Tsinghua University, Beijing, China.
  • Xiangru Chen
    Beijing XiaoBaiShiJi Network Technical Co., Ltd, Beijing, 100084, China.
  • Keng-Leong Ang
    Department of Thoracic Surgery, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Yuwei He
    Beijing National Research Center for Information Science and Technology (BNRist), Tsinghua University, Beijing, 100084, China.
  • Na Jiang
    Center for Public Health Research, Medical School of Nanjing University, Nanjing, People's Republic of China.
  • Qiang Du
    Department of Medical Imaging, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.
  • Qingsi Zeng
    National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Ligong Lu
    Zhuhai People Hospital, Zhuhai, China.
  • Zebin Gao
    Beijing XiaoBaiShiJi Network Technical Co., Ltd, Beijing, 100084, China.
  • Linduo Li
    College of Engineering, Northeastern University, 360 Huntington Ave., Boston, MA, 02115, USA.
  • Quanzheng Li
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
  • Fangxing Nie
    Xiaobaishiji, Beijing, China.
  • Guiguang Ding
    Institute for Brain and Cognitive Sciences, Tsinghua University, Beijing, 100084, China.
  • Gao Huang
    Department of Automation, Tsinghua University, Beijing 100084, China. huang-g09@mails.tsinghua.edu.cn
  • Ailan Chen
    China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Yimin Li
    Department of Radiation Oncology, University of California Davis Medical Center, Sacramento, CA, United States.
  • Weijie Guan
    China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Ling Sang
  • Yuanda Xu
  • Huai Chen
    Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.
  • Zisheng Chen
    China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Shiyue Li
    China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Nuofu Zhang
    China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Ying Chen
    Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Danxia Huang
    National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Run Li
    School of Nursing, Shanxi University of Chinese Medicine, Shanxi, Taiyuan 030024, China.
  • Jianfu Li
    Mayo Clinic.
  • Bo Cheng
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Yi Zhao
    Department of Biostatistics and Health Data Science, Indiana University School of Medicine.
  • Caichen Li
    National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Shan Xiong
    Shandong Academy of Medical Sciences, Institute of Materia Medica, Ji'nan 250062, People's Republic of China.
  • Runchen Wang
    National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Jun Liu
    Department of Radiology, Second Xiangya Hospital, Changsha, Hunan, China.
  • Wei Wang
    State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China.
  • Jun Huang
    Department of Endoscopy, Jiangxi Cancer Hospital, Nanchang, China.
  • Fei Cui
    Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China.
  • Tao Xu
    Department of Urology, Peking University People's Hospital, Beijing, China.
  • Fleming Y M Lure
    Shenzhen Zhiying Medical Imaging, Shenzhen, Guangdong, China.
  • Meixiao Zhan
    Zhuhai Interventional Medical Center, Zhuhai Precision Medical Center, Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, Jinan University, Zhuhai, Guangdong 519000, PR China. Electronic address: zhanmeixiao1987@126.com.
  • Yuanyi Huang
  • Qiang Yang
  • Qionghai Dai
  • Wenhua Liang
    Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Jianxing He
    Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China.
  • Nanshan Zhong
    Guangzhou National Laboratory, Guangzhou, China.