Assessment of deep learning algorithms to predict histopathological diagnosis of breast cancer: first Moroccan prospective study on a private dataset.

Journal: BMC research notes
Published Date:

Abstract

OBJECTIVE: Breast cancer is a critical public health issue and a leading cause of cancer-related deaths among women worldwide. Its early diagnosis and detection can effectively help in increasing the chances of survival rate. For this reason, the diagnosis and classification of breast cancer using Deep learning algorithms have attracted a lot of attention. Therefore, our study aimed to design a computational approach based on deep convolutional neural networks for an efficient classification of breast cancer histopathological images by using our own created dataset. We collected overall 328 digital slides, from 116 of surgical breast specimens diagnosed with invasive breast carcinoma of non-specific type, and referred to the histopathology department of the National Institute of Oncology in Rabat, Morocco. We used two models of deep neural network architectures in order to accurately classify the images into one of three categories: normal tissue-benign lesions, in situ carcinoma or invasive carcinoma.

Authors

  • H El Agouri
    Pathology Department, Oncology National Institute, Faculty of Medicine and Pharmacy, Mohammed V University, 10100, Rabat, Morocco. hajar.elagouri@gmail.com.
  • M Azizi
    Datapathology, 20000, Casablanca, Morocco.
  • H El Attar
    Anatomic Pathology Laboratory Ennassr, 24000, El Jadida, Morocco.
  • M El Khannoussi
    Datapathology, 20000, Casablanca, Morocco.
  • A Ibrahimi
    Medical Biotechnology Laboratory (MedBiotech), Bioinova Research Center, Rabat Medical & Pharmacy School, Mohammed Vth University in Rabat, 10100, Rabat, Morocco.
  • R Kabbaj
    Pathology Department, Oncology National Institute, Faculty of Medicine and Pharmacy, Mohammed V University, 10100, Rabat, Morocco.
  • H Kadiri
    Pathology Department, Oncology National Institute, Faculty of Medicine and Pharmacy, Mohammed V University, 10100, Rabat, Morocco.
  • S BekarSabein
    Pathology Department, Oncology National Institute, Faculty of Medicine and Pharmacy, Mohammed V University, 10100, Rabat, Morocco.
  • S EchCharif
    Pathology Department, Oncology National Institute, Faculty of Medicine and Pharmacy, Mohammed V University, 10100, Rabat, Morocco.
  • C Mounjid
    Pathology Department, Oncology National Institute, Faculty of Sciences, Mohammed V University, 10100, Rabat, Morocco.
  • B El Khannoussi
    Pathology Department, Oncology National Institute, Faculty of Medicine and Pharmacy, Mohammed V University, 10100, Rabat, Morocco.