Improved-Mask R-CNN: Towards an accurate generic MSK MRI instance segmentation platform (data from the Osteoarthritis Initiative).

Journal: Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Published Date:

Abstract

INTRODUCTION: Objective assessment of osteoarthritis (OA) Magnetic Resonance Imaging (MRI) scans can address the limitations of the current OA assessment approaches. Detecting and extracting bone, cartilage, and joint fluid is a necessary component for the objective assessment of OA, which helps to quantify tissue characteristics such as volume and thickness. Many algorithms, based on Artificial Intelligence (AI), have been proposed over recent years for segmenting bone and soft tissues. Most of these segmentation methods suffer from the class imbalance problem, can't differentiate between the same anatomic structure, or do not support segmenting different rang of tissue sizes. Mask R-CNN is an instance segmentation framework, meaning it segments and distinct each object of interest like different anatomical structures (e.g. bone and cartilage) using a single model. In this study, the Mask R-CNN architecture was deployed to address the need for a segmentation method that is applicable to use for different tissue scales, pathologies, and MRI sequences associated with OA, without having a problem with imbalanced classes. In addition, we modified the Mask R-CNN to improve segmentation accuracy around instance edges.

Authors

  • Banafshe Felfeliyan
    Biomedical Engineering, Schulich School of Engineering, University of Calgary, Canada.
  • Abhilash Hareendranathan
    Department of Radiology & Diagnostic Imaging, University of Alberta, 2A2.41 WMC, 8440 - 112 St. NW, Edmonton, AB, Canada.
  • Gregor Kuntze
    McCaig Institute for Bone and Joint Health University of Calgary, Calgary, Canada.
  • Jacob L Jaremko
    Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
  • Janet L Ronsky
    Mechanical & Manufacturing Engineering, Schulich School of Engineering, University of Calgary.