Osteoarthritis (OA) is a complex disorder driven by the combination of environmental and genetic factors. Given its high global prevalence and heterogeneity, developing effective and personalized treatment methods is crucial. This requires identifyin...
OBJECTIVE: To explore the ability of natural language processing (NLP) methods to identify confounder information beyond what can be identified using claims codes alone for pharmacoepidemiology.
Machine learning can be applied to identify key genes associated with osteoarthritis (OA). This study aimed to explore the differential expression of necroptosis-related genes (NRGs) during the progression of OA, identify key gene modules strongly li...
Artificial cells, nanomedicine, and biotechnology
40022676
Ageing significantly contributes to osteoarthritis (OA) and metabolic syndrome (MetS) pathogenesis, yet the underlying mechanisms remain unknown. This study aimed to identify ageing-related biomarkers in OA patients with MetS. OA and MetS datasets an...
Osteoarthritis is a degenerative condition that affects bones and cartilage, often leading to structural changes, including osteophyte formation, bone density loss, and the narrowing of joint spaces. Over time, this process may disrupt the glenohumer...
Osteoarthritis is a widespread chronic joint disease, becoming increasingly prevalent, particularly among individuals over the age of 45. This condition causes joint pain and dysfunction, significantly disrupting daily life. The objective of this stu...
Osteoarthritis (OA) is a degenerative joint disease with significant clinical and societal impact. Traditional diagnostic methods, including subjective clinical assessments and imaging techniques such as X-rays and MRIs, are often limited in their ab...
Journal of orthopaedic surgery and research
40247403
BACKGROUND: Osteoarthritis (OA) is the leading cause of degenerative joint disease, with total joint replacement as the only definitive cure. However, no disease-modifying therapy is currently available. Inflammation and fibrosis in the infrapatellar...
Computer methods and programs in biomedicine
40239454
BACKGROUND: Osteoarthritis (OA) is a common degenerative joint disease, particularly affecting individuals aged >50 years. It deteriorates quality of life and restricts physical activity in the elderly. Early diagnosis of OA is crucial for effective ...
OBJECTIVES: This study aimed to evaluate the effectiveness of deep learning method for denoising and artefact reduction (AR) in zero echo time MRI (ZTE-MRI). Also, clinical applicability was evaluated by comparing image diagnosis to the temporomandib...