Technical note: A PET/MR coil with an integrated, orbiting 511 keV transmission source for PET/MR imaging validated in an animal study.

Journal: Medical physics
Published Date: Mar 8, 2022

Abstract

BACKGROUND: MR-based methods for attenuation correction (AC) in PET/MRI either neglect attenuation of bone, or use MR-signal derived information about bone, which leads to a bias in quantification of tracer uptake in PET. In a previous study, we presented a PET/MRI specific MR coil with an integrated transmission source (TX) system allowing for direct measurement of attenuation. In phantom measurements, this system successfully reproduced the linear attenuation coefficient of water.

Authors

  • Andreas Renner
    Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Vienna, Austria.
  • Ivo Rausch
    Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Vienna, Austria.
  • Jacobo Cal Gonzalez
    Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Vienna, Austria.
  • Elmar Laistler
    Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Vienna, Austria.
  • Ewald Moser
    Center for Medical Physics and Biomedical Engineering, Medical University of ViennaVienna, Austria; MR Centre of Excellence, Medical University of ViennaVienna, Austria; Brain Behaviour Laboratory, Department of Psychiatry, University of Pennsylvania Medical CenterPhiladelphia, PA, USA.
  • Thies Jochimsen
    Department of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
  • Tatjana Sattler
    Clinic for Ruminants and Swine, University of Leipzig, Leipzig, Germany.
  • Osama Sabri
    Department of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
  • Thomas Beyer
    QIMP Group, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
  • Michael Figl
    Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Vienna, Austria.
  • Wolfgang Birkfellner
    Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Vienna, Austria.
  • Bernhard Sattler
    Department of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.

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