Utilizing Deep Learning to Analyze Whole Slide Images of Colonic Biopsies for Associations Between Eosinophil Density and Clinicopathologic Features in Active Ulcerative Colitis.

Journal: Inflammatory bowel diseases
PMID: 34106256

Abstract

BACKGROUND: Eosinophils have been implicated in the pathogenesis of ulcerative colitis and have been associated with disease course and therapeutic response. However, associations between eosinophil density, histologic activity, and clinical features have not been rigorously studied.

Authors

  • Niels Vande Casteele
    Department of Medicine, University of California San Diego, La Jolla, California, USA.
  • Jonathan A Leighton
    Division of Gastroenterology and Hepatology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.
  • Shabana F Pasha
    Division of Gastroenterology and Hepatology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.
  • Frank Cusimano
    Division of Gastroenterology and Hepatology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.
  • Aart Mookhoek
    Department of Pathology, VU Medical Center, Amsterdam, the Netherlands.
  • Catherine E Hagen
    Department of Pathology and Laboratory Medicine, Mayo Clinic Rochester, Rochester, Minnesota, USA.
  • Christophe Rosty
    Colorectal Oncogenomics Group, Department of Clinical Pathology, University of Melbourne, Parkville, Victoria, Australia.
  • Reetesh K Pai
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Rish K Pai
    Department of Pathology and Laboratory Medicine, Mayo Clinic Arizona, Scottsdale, AZ, USA.

Keywords

External Resources

Popular Topics
Recent Journals