Recent advances and clinical applications of deep learning in medical image analysis.

Journal: Medical image analysis
Published Date:

Abstract

Deep learning has received extensive research interest in developing new medical image processing algorithms, and deep learning based models have been remarkably successful in a variety of medical imaging tasks to support disease detection and diagnosis. Despite the success, the further improvement of deep learning models in medical image analysis is majorly bottlenecked by the lack of large-sized and well-annotated datasets. In the past five years, many studies have focused on addressing this challenge. In this paper, we reviewed and summarized these recent studies to provide a comprehensive overview of applying deep learning methods in various medical image analysis tasks. Especially, we emphasize the latest progress and contributions of state-of-the-art unsupervised and semi-supervised deep learning in medical image analysis, which are summarized based on different application scenarios, including classification, segmentation, detection, and image registration. We also discuss major technical challenges and suggest possible solutions in the future research efforts.

Authors

  • Xuxin Chen
    School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
  • Ximin Wang
    School of Information Science and Technology, ShanghaiTech University, Shanghai 201210, China.
  • Ke Zhang
    Center for Radiation Oncology, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou 310001, China.
  • Kar-Ming Fung
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Theresa C Thai
    Department of Radiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
  • Kathleen Moore
    Health Science Center of University of Oklahoma, Oklahoma City, OK 73104, United States.
  • Robert S Mannel
    Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Hong Liu
    Key Laboratory of Grain and Oil Processing and Food Safety of Sichuan Province, College of Food and Bioengineering, Xihua University Chengdu 610039 China xingyage1@163.com.
  • Bin Zheng
    School of Electrical and Computer Engineering, University of Oklahoma, 101 David L. Boren Blvd, Norman, OK, 73019, USA.
  • Yuchen Qiu
    School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA.