Predictors of Toxicity Among Older Adults with Cancer.

Journal: Seminars in radiation oncology
Published Date:

Abstract

An increasing number of cancer patients are of advanced age as the incidence of cancer increases with age. In this article, the clinical predictors of toxicity that may help in treatment selection are addressed, as well as mitigators of toxicity. The potential of artificial intelligence to enable further progress in the understanding of the interaction of age and tolerance to radiation is reviewed. The final section reviews the literature on patient-related outcomes for older patients.

Authors

  • Martine Extermann
    Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, FL. Electronic address: martine.extermann@moffitt.org.
  • Indrin J Chetty
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan, USA.
  • Stephen L Brown
    Department of Radiation Oncology, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, MI.
  • Mohammed Al-Jumayli
    Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, FL.
  • Benjamin Movsas
    Department of Radiation Oncology, Josephine Ford Cancer Institute, Henry Ford Health System, Detroit, Michigan.