Named Entity Recognition in Pubmed Abstracts for Pharmacovigilance Using Deep Learning.

Journal: Studies in health technology and informatics
Published Date:

Abstract

Methods of natural language processing associated with machine learning or deep learning can support detection of adverse drug reactions in abstracts of case reports available on Pubmed. In 2012, Gurulingappa et al. proposed a training set for the recognition of named entities corresponding to drugs and adverse reactions on 3000 Pubmed abstracts. We implemented a classifier using deep learning with a Bi-LSTM and a CRF layer that achieves an F-measure of 87.8%. Perspectives consist in using BERT for improving the classifier, and applying it to a large number of Pubmed abstract to build a database of case reports available in the literature.

Authors

  • T Trang Nghiem
    Institute of Thermal, Mechanical and Material Sciences (ITheMM EA 7548), University of Reims Champagne-Ardenne, 51687 Reims, France.
  • Cédric Bousquet
    Sorbonne Université, INSERM, Université Paris 13, LIMICS, Paris, France.