Survival Prediction After Neurosurgical Resection of Brain Metastases: A Machine Learning Approach.

Journal: Neurosurgery
Published Date:

Abstract

BACKGROUND: Current prognostic models for brain metastases (BMs) have been constructed and validated almost entirely with data from patients receiving up-front radiotherapy, leaving uncertainty about surgical patients.

Authors

  • Alexander F C Hulsbergen
    Department of Neurosurgery, Computational Neurosciences Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, Haaglanden Medical Center, The Hague, The Netherlands; Department of Neurosurgery, Leiden Medical Center, Leiden, The Netherlands.
  • Yu Tung Lo
    Computational Neuroscience Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Ilia Awakimjan
    Computational Neuroscience Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Vasileios K Kavouridis
    Department of Neurosurgery, Computational Neuroscience Outcomes Center, Brigham and Women's Hospital, Boston, Massachusetts.
  • John G Phillips
    Harvard Radiation Oncology Program, Boston, Massachusetts; Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts.
  • Timothy R Smith
    Computational Neurosciences Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Joost J C Verhoeff
    Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Kun-Hsing Yu
    Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Marike L D Broekman
    Department of Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands; Computational Neurosciences Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Omar Arnaout
    Computational Neurosciences Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: oarnaout@bwh.harvard.edu.