A deep learning-based precision and automatic kidney segmentation system using efficient feature pyramid networks in computed tomography images.

Journal: Computer methods and programs in biomedicine
Published Date:

Abstract

This paper proposes an encoder-decoder architecture for kidney segmentation. A hyperparameter optimization process is implemented, including the development of a model architecture, selecting a windowing method and a loss function, and data augmentation. The model consists of EfficientNet-B5 as the encoder and a feature pyramid network as the decoder that yields the best performance with a Dice score of 0.969 on the 2019 Kidney and Kidney Tumor Segmentation Challenge dataset. The proposed model is tested with different voxel spacing, anatomical planes, and kidney and tumor volumes. Moreover, case studies are conducted to analyze segmentation outliers. Finally, five-fold cross-validation and the 3D-IRCAD-01 dataset are used to evaluate the developed model in terms of the following evaluation metrics: the Dice score, recall, precision, and the Intersection over Union score. A new development and application of artificial intelligence algorithms to solve image analysis and interpretation will be demonstrated in this paper. Overall, our experiment results show that the proposed kidney segmentation solutions in CT images can be significantly applied to clinical needs to assist surgeons in surgical planning. It enables the calculation of the total kidney volume for kidney function estimation in ADPKD and supports radiologists or doctors in disease diagnoses and disease progression.

Authors

  • Chiu-Han Hsiao
    Research Center for Information Technology Innovation, Academia Sinica, Taipei City, Taiwan, ROC.
  • Ping-Cherng Lin
    Research Center for Information Technology Innovation, Academia Sinica, Taipei City, Taiwan, ROC.
  • Li-An Chung
    Research Center for Information Technology Innovation, Academia Sinica, Taipei City, (R.O.C.) Taiwan.
  • Frank Yeong-Sung Lin
    Department of Information Management, National Taiwan University, Taipei City, Taiwan, ROC.
  • Feng-Jung Yang
    Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Douliu City, Yunlin County; School of Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC. Electronic address: fongrong@ntu.edu.tw.
  • Shao-Yu Yang
    Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan, ROC.
  • Chih-Horng Wu
    Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan.
  • Yennun Huang
    Research Center for Information Technology Innovation, Academia Sinica, Taipei 10607, Taiwan.
  • Tzu-Lung Sun
    Department of Information Management, National Taiwan University, Taipei City, Taiwan, ROC.