Multi-class retinal fluid joint segmentation based on cascaded convolutional neural networks.

Journal: Physics in medicine and biology
Published Date:

Abstract

. Retinal fluid mainly includes intra-retinal fluid (IRF), sub-retinal fluid (SRF) and pigment epithelial detachment (PED), whose accurate segmentation in optical coherence tomography (OCT) image is of great importance to the diagnosis and treatment of the relative fundus diseases.. In this paper, a novel two-stage multi-class retinal fluid joint segmentation framework based on cascaded convolutional neural networks is proposed. In the pre-segmentation stage, a U-shape encoder-decoder network is adopted to acquire the retinal mask and generate a retinal relative distance map, which can provide the spatial prior information for the next fluid segmentation. In the fluid segmentation stage, an improved context attention and fusion network based on context shrinkage encode module and multi-scale and multi-category semantic supervision module (named as ICAF-Net) is proposed to jointly segment IRF, SRF and PED.. the proposed segmentation framework was evaluated on the dataset of RETOUCH challenge. The average Dice similarity coefficient, intersection over union and accuracy (Acc) reach 76.39%, 64.03% and 99.32% respectively.. The proposed framework can achieve good performance in the joint segmentation of multi-class fluid in retinal OCT images and outperforms some state-of-the-art segmentation networks.

Authors

  • Wei Tang
    Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Yanqing Ye
    MIPAV Lab, School of Electronic and Information Engineering, Soochow University, Jiangsu 215006, People's Republic of China.
  • Xinjian Chen
    Medical Image Processing, Analysis, and Visualization (MIVAP) Lab, School of Electronics and Information Engineering, Soochow University, Suzhou, China.
  • Fei Shi
    Medical Image Processing, Analysis, and Visualization (MIVAP) Lab, School of Electronics and Information Engineering, Soochow University, Suzhou, China.
  • Dehui Xiang
  • Zhongyue Chen
    MIPAV Lab, School of Electronic and Information Engineering, Soochow University, Jiangsu 215006, People's Republic of China.
  • Weifang Zhu