Unsupervised Deep Learning for Stroke Lesion Segmentation on Follow-up CT Based on Generative Adversarial Networks.

Journal: AJNR. American journal of neuroradiology
PMID:

Abstract

BACKGROUND AND PURPOSE: Supervised deep learning is the state-of-the-art method for stroke lesion segmentation on NCCT. Supervised methods require manual lesion annotations for model development, while unsupervised deep learning methods such as generative adversarial networks do not. The aim of this study was to develop and evaluate a generative adversarial network to segment infarct and hemorrhagic stroke lesions on follow-up NCCT scans.

Authors

  • H van Voorst
    From the Departments of Radiology and Nuclear Medicine (H.v.V., P.R.K., L.M.v.P., B.J.E., C.B.L.M.M., H.A.M.) h.vanvoorst@amsterdamumc.nl.
  • P R Konduri
    From the Departments of Radiology and Nuclear Medicine (H.v.V., P.R.K., L.M.v.P., B.J.E., C.B.L.M.M., H.A.M.).
  • L M van Poppel
    From the Departments of Radiology and Nuclear Medicine (H.v.V., P.R.K., L.M.v.P., B.J.E., C.B.L.M.M., H.A.M.).
  • W van der Steen
    Departments of Neurology (W.v.d.S., P.M.v.d.S.).
  • P M van der Sluijs
    Departments of Neurology (W.v.d.S., P.M.v.d.S.).
  • E M H Slot
    Department of Neurology and Neurosurgery (E.M.H.S.), University Medical Center Utrecht, Utrecht, the Netherlands.
  • B J Emmer
    Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • W H van Zwam
    Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Y B W E M Roos
    Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • C B L M Majoie
    Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • G Zaharchuk
    From the Departments of Radiology (G.Z., M.W., D.R., C.P.L.) gregz@stanford.edu.
  • M W A Caan
    Biomedical Engineering and Physics (H.v.V., P.R.K., L.M.v.P., M.W.A.C., H.A.M.).
  • H A Marquering
    Department of Biomedical Engineering and Physics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.