AIMC Topic: Ischemic Stroke
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Metabolomic biomarkers could be molecular clocks in timing stroke onset.
Scientific reports
Jul 1, 2025
The preferred treatment for acute ischaemic stroke (AIS) is intravenous thrombolysis (IVT) administered within 4.5 hours (h) of symptom onset. This study aimed to identify metabolomic biomarkers for distinguishing AIS patients within 4.5 h of symptom...
Comparison of lesion segmentation performance in diffusion-weighted imaging and apparent diffusion coefficient images of stroke by artificial neural networks.
PloS one
Jun 9, 2025
Stroke is the second leading cause of death, accounting for 11% of deaths worldwide. Comparing diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) images is important for stroke diagnosis, but most studies have focused on lesion...
Research on ischemic stroke risk assessment based on CTA radiomics and machine learning.
BMC medical imaging
Jun 5, 2025
BACKGROUND: The study explores the value of a model constructed by integrating CTA-based carotid plaque radiomic features, clinical risk factors, and plaque imaging characteristics for prognosticating the risk of ischemic stroke.
Bioinformatics prediction of function of T-cell exhaustion related genes in ischemic stroke.
Scientific reports
May 29, 2025
Ischemic stroke (IS) is a multifactorial disease caused by the interaction of a variety of environmental and genetic factors, which can lead to severe disability and heavy social burden. This study aimed to find potential biomarkers related to T cell...
Advanced predictive modeling for enhanced mortality prediction in ICU stroke patients using clinical data.
PloS one
May 28, 2025
Background Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in intensive care u...
Benchmarking reinforcement learning algorithms for autonomous mechanical thrombectomy.
International journal of computer assisted radiology and surgery
Apr 29, 2025
PURPOSE: Mechanical thrombectomy (MT) is the gold standard for treating acute ischemic stroke. However, challenges such as operator radiation exposure, reliance on operator experience, and limited treatment access remain. Although autonomous robotics...
Identification and Validation of Glycosylation‑Related Genes in Ischemic Stroke Based on Bioinformatics and Machine Learning.
Journal of molecular neuroscience : MN
Apr 29, 2025
Ischemic stroke (IS) constitutes a severe neurological disorder with restricted treatment alternatives. Recent investigations have disclosed that glycosylation is closely associated with the occurrence and outcome of IS. Nevertheless, data on the tra...
Integrating WGCNA and SVM-RFE identifies hub molecular biomarkers driving ischemic stroke progression.
Neurological research
Apr 22, 2025
BACKGROUND: Stroke is the second most common cause of death worldwide and the leading cause of long-term severe disability with neurological impairment worsening within hours after stroke onset and being especially involved with motor function. So fa...
Quantitative Ischemic Lesions of Portable Low-Field Strength MRI Using Deep Learning-Based Super-Resolution.
Stroke
Apr 16, 2025
BACKGROUND: Deep learning-based synthetic super-resolution magnetic resonance imaging (SynthMRI) may improve the quantitative lesion performance of portable low-field strength magnetic resonance imaging (LF-MRI). The aim of this study is to evaluate ...
Risk Factors and Outcomes of Hemorrhagic Transformation in Acute Ischemic Stroke Following Thrombolysis: Analysis of a Single-Center Experience and Review of the Literature.
Medicina (Kaunas, Lithuania)
Apr 14, 2025
: This is a retrospective study conducted at the Clinical County Hospital of Craiova, Romania, providing valuable insights into hemorrhagic transformation (HT) in thrombolyzed patients with acute ischemic stroke (AIS). Hemorrhagic complications remai...
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