AIMC Topic: Ischemic Stroke
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Age-related variation in hemoglobin glycation index and stroke mortality: mediation and machine learning in a cohort study.
Scientific reports
Aug 2, 2025
To investigate the associations between both age and the hemoglobin glycation index (HGI) and the 30-day and 1-year mortality in ischemic stroke (IS) patients and to analyze the mediating effect of the HGI on the relationship between age and mortalit...
Deep learning to identify stroke within 4.5 h using DWI and FLAIR in a prospective multicenter study.
Scientific reports
Jul 19, 2025
To enhance thrombolysis eligibility in acute ischemic stroke, we developed a deep learning model to estimate stroke onset within 4.5 h using diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) images. Given the variabilit...
Analyses of the mechanism and therapeutic targets of senescence related genes in ischemic stroke with multi-omics approach.
Scientific reports
Jul 18, 2025
Ischemic stroke (IS) affects 11 million people annually, posing substantial clinical and economic burdens. Current therapies remain limited by time sensitivity and variable efficacy, necessitating novel biomarkers. We developed a multi-omics framewor...
A machine learning model reveals invisible microscopic variation in acute ischaemic stroke (≤ 6 h) with non-contrast computed tomography.
BMC medical imaging
Jul 9, 2025
BACKGROUND: In most medical centers, particularly in primary hospitals, non-contrast computed tomography (NCCT) serves as the primary imaging modality for diagnosing acute ischemic stroke. However, due to the small density difference between the infa...
Machine learning-based prognostic prediction for acute ischemic stroke using whole-brain and infarct multi-PLD ASL radiomics.
BMC medical imaging
Jul 4, 2025
INTRODUCTION: Accurate early prognostic prediction for acute ischemic stroke (AIS) is essential for guiding personalized treatment. This study aimed to assess the predictive value of radiomics features from whole-brain and infarct cerebral blood flow...
Metabolomic biomarkers could be molecular clocks in timing stroke onset.
Scientific reports
Jul 1, 2025
The preferred treatment for acute ischaemic stroke (AIS) is intravenous thrombolysis (IVT) administered within 4.5 hours (h) of symptom onset. This study aimed to identify metabolomic biomarkers for distinguishing AIS patients within 4.5 h of symptom...
Comparison of lesion segmentation performance in diffusion-weighted imaging and apparent diffusion coefficient images of stroke by artificial neural networks.
PloS one
Jun 9, 2025
Stroke is the second leading cause of death, accounting for 11% of deaths worldwide. Comparing diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) images is important for stroke diagnosis, but most studies have focused on lesion...
Research on ischemic stroke risk assessment based on CTA radiomics and machine learning.
BMC medical imaging
Jun 5, 2025
BACKGROUND: The study explores the value of a model constructed by integrating CTA-based carotid plaque radiomic features, clinical risk factors, and plaque imaging characteristics for prognosticating the risk of ischemic stroke.
Bioinformatics prediction of function of T-cell exhaustion related genes in ischemic stroke.
Scientific reports
May 29, 2025
Ischemic stroke (IS) is a multifactorial disease caused by the interaction of a variety of environmental and genetic factors, which can lead to severe disability and heavy social burden. This study aimed to find potential biomarkers related to T cell...
Advanced predictive modeling for enhanced mortality prediction in ICU stroke patients using clinical data.
PloS one
May 28, 2025
Background Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in intensive care u...
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