Detection of live breast cancer cells in bright-field microscopy images containing white blood cells by image analysis and deep learning.

Journal: Journal of biomedical optics
Published Date: Jul 1, 2022

Abstract

SIGNIFICANCE: Circulating tumor cells (CTCs) are important biomarkers for cancer management. Isolated CTCs from blood are stained to detect and enumerate CTCs. However, the staining process is laborious and moreover makes CTCs unsuitable for drug testing and molecular characterization.

Authors

  • Golnaz Moallem
    Texas Tech University, Department of Electrical and Computer Engineering, Lubbock, Texas, United States.
  • Adity A Pore
    Texas Tech University, Department of Chemical Engineering, Lubbock, Texas, United States.
  • Anirudh Gangadhar
    Texas Tech University, Department of Chemical Engineering, Lubbock, Texas, United States.
  • Hamed Sari-Sarraf
    Texas Tech University, Department of Electrical and Computer Engineering, Lubbock, Texas, United States.
  • Siva A Vanapalli
    Department of Chemical Engineering, Texas Tech University, Lubbock, TX, United States.

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