Enhancing MR image segmentation with realistic adversarial data augmentation.

Journal: Medical image analysis
Published Date:

Abstract

The success of neural networks on medical image segmentation tasks typically relies on large labeled datasets for model training. However, acquiring and manually labeling a large medical image set is resource-intensive, expensive, and sometimes impractical due to data sharing and privacy issues. To address this challenge, we propose AdvChain, a generic adversarial data augmentation framework, aiming at improving both the diversity and effectiveness of training data for medical image segmentation tasks. AdvChain augments data with dynamic data augmentation, generating randomly chained photo-metric and geometric transformations to resemble realistic yet challenging imaging variations to expand training data. By jointly optimizing the data augmentation model and a segmentation network during training, challenging examples are generated to enhance network generalizability for the downstream task. The proposed adversarial data augmentation does not rely on generative networks and can be used as a plug-in module in general segmentation networks. It is computationally efficient and applicable for both low-shot supervised and semi-supervised learning. We analyze and evaluate the method on two MR image segmentation tasks: cardiac segmentation and prostate segmentation with limited labeled data. Results show that the proposed approach can alleviate the need for labeled data while improving model generalization ability, indicating its practical value in medical imaging applications.

Authors

  • Chen Chen
    The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Chen Qin
  • Cheng Ouyang
  • Zeju Li
    Department of Electronic Engineering, Fudan University, Shanghai, China.
  • Shuo Wang
    College of Tea & Food Science, Anhui Agricultural University, Hefei, China.
  • Huaqi Qiu
  • Liang Chen
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
  • Giacomo Tarroni
    Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK.
  • Wenjia Bai
    Department of Computing Imperial College London London UK.
  • Daniel Rueckert
    Biomedical Image Analysis (BioMedIA) Group, Department of Computing, Imperial College London, UK. Electronic address: d.rueckert@imperial.ac.uk.