A Machine Learning-Based Intrauterine Growth Restriction (IUGR) Prediction Model for Newborns.

Journal: Indian journal of pediatrics
PMID:

Abstract

Intrauterine growth restriction (IUGR) is a condition in which the fetal weight is below the 10th percentile for its gestational age. Prenatal exposure to metals can cause a decrease in fetal growth during gestation thereby reducing birth weight. Therefore, the aim of the present study was to develop a machine learning model for early prediction of IUGR. A total of 126 IUGR and 88 appropriate-for-gestational-age (AGA) samples were collected from the Gynecology Department, Safdarjung Hospital, New Delhi. The predictive models were developed using the Weka software. The models developed using all the features gave the highest accuracy of 95.5% with support vector machine (SMO) algorithm and 88.5% with multilayer perceptron (MLP) algorithm. Further, models developed after feature selection using 14 important and statistically significant variables also gave the highest accuracy of 98.5% with SMO algorithm and 99% with Naïve Bayes (NB) algorithm. The study concluded SMO_31, SMO_14, MLP_31, and NB_14 to be the better classifiers for IUGR prediction.

Authors

  • Ravi Deval
    Electron Microscopy and Environmental Toxicology Lab, ICMR - National Institute of Pathology, New Delhi, 110029, India.
  • Pallavi Saxena
    Electron Microscopy and Environmental Toxicology Lab, ICMR - National Institute of Pathology, New Delhi, 110029, India.
  • Dibyabhaba Pradhan
    Division of Biomedical Informatics, ICMR - Computational Genomics Centre, New Delhi, India.
  • Ashwani Kumar Mishra
    National Drug Dependence Treatment Center, AIIMS, New Delhi, India.
  • Arun Kumar Jain
    Electron Microscopy and Environmental Toxicology Lab, ICMR - National Institute of Pathology, New Delhi, 110029, India. drakjain@gmail.com.