Identifying neurocognitive disorder using vector representation of free conversation.

Journal: Scientific reports
PMID:

Abstract

In recent years, studies on the use of natural language processing (NLP) approaches to identify dementia have been reported. Most of these studies used picture description tasks or other similar tasks to encourage spontaneous speech, but the use of free conversation without requiring a task might be easier to perform in a clinical setting. Moreover, free conversation is unlikely to induce a learning effect. Therefore, the purpose of this study was to develop a machine learning model to discriminate subjects with and without dementia by extracting features from unstructured free conversation data using NLP. We recruited patients who visited a specialized outpatient clinic for dementia and healthy volunteers. Participants' conversation was transcribed and the text data was decomposed from natural sentences into morphemes by performing a morphological analysis using NLP, and then converted into real-valued vectors that were used as features for machine learning. A total of 432 datasets were used, and the resulting machine learning model classified the data for dementia and non-dementia subjects with an accuracy of 0.900, sensitivity of 0.881, and a specificity of 0.916. Using sentence vector information, it was possible to develop a machine-learning algorithm capable of discriminating dementia from non-dementia subjects with a high accuracy based on free conversation.

Authors

  • Toshiro Horigome
    Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
  • Kimihiro Hino
    FRONTEO Healthcare Inc, Tokyo, Japan.
  • Hiroyoshi Toyoshiba
    FRONTEO Healthcare Inc, Tokyo, Japan.
  • Norihisa Shindo
    Lifescience AI Business Division, Research Development Department, FRONTEO Inc, Tokyo, Japan.
  • Kei Funaki
    Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
  • Yoko Eguchi
    Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
  • Momoko Kitazawa
    Department of Psychiatry, School of Medicine, Keio University, Tokyo 160-8582, Japan.
  • Takanori Fujita
    World Economic Forum Centre for the Fourth Industrial Revolution Japan, Project Lead for Healthcare Data Policy.
  • Masaru Mimura
    Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
  • Taishiro Kishimoto
    Hills Joint Research Laboratory for Future Preventive Medicine and Wellness, Keio University School of Medicine, Tokyo, Japan.