Learning low-dose CT degradation from unpaired data with flow-based model.
Journal:
Medical physics
Published Date:
Aug 8, 2022
Abstract
BACKGROUND: There has been growing interest in low-dose computed tomography (LDCT) for reducing the X-ray radiation to patients. However, LDCT always suffers from complex noise in reconstructed images. Although deep learning-based methods have shown their strong performance in LDCT denoising, most of them require a large number of paired training data of normal-dose CT (NDCT) images and LDCT images, which are hard to acquire in the clinic. Lack of paired training data significantly undermines the practicability of supervised deep learning-based methods. To alleviate this problem, unsupervised or weakly supervised deep learning-based methods are required.