The antifibrotic effect of isolate tagitinin C from tithonia diversifolia (Hemsley) A. Gray on keloid fibroblast cell.

Journal: The Pan African medical journal

PMID: 30637049

Abstract

INTRODUCTION: Keloids characterized by fibroblast hyperproliferation and depositions of collagen which similar to cancer cells. Tagitinin C is a class of sesquiterpene lactones (SLS) was isolated from the leaves of the moon flower (Hemsley) A. Gray. The study aim is to evaluate the effects of tagitinin C from to keloid fibroblasts (KF).

Authors

Imaniar Ranti

Department of Pharmacology, Faculty of Medicine and Health Science,Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia.
Mae Sri Hartati Wahyuningsih

Department of Pharmacology, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Yohannes Widodo Wirohadidjojo

Department of Dermatology and Venerology, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Keywords

Asteraceae Cell Proliferation Cell Survival Cells, Cultured Collagen Dose-Response Relationship, Drug Enzyme-Linked Immunosorbent Assay Fibroblasts Humans Inhibitory Concentration 50 Keloid Mitomycin Sesquiterpenes Time Factors

External Resources

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The antifibrotic effect of isolate tagitinin C from tithonia diversifolia (Hemsley) A. Gray on keloid fibroblast cell.

Abstract

Authors

Keywords

External Resources

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