Population movements constitute a significant driver of cultural change in prehistoric societies. In recent years, sulfur isotopes have emerged as a valuable approach for distinguishing human/animal provenance. However, the scarcity of sulfur isotope...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Aug 15, 2025
Vascular aging-related remodeling is a common pathological basis for many chronic diseases, so early detection of physical arterial aging is important for their prevention and control. Existing staining methods can only analyze a limited number of ti...
Degenerative joint diseases are major contributors to pain, impaired mobility, and an increasing socioeconomic burden in aging populations. Tissue Engineering (TE) offers alternative solutions to restore joint functions. However, current TE approache...
Collagen peptides are ubiquitously applied in food systems for their versatile bioactivities but face constraints from labor-intensive enzymatic screening and zoonotic risks from terrestrial sources. This study developed machine learning (ML) models ...
In this study, we explore the potential of ten quantitative (radiofrequency-based) ultrasound parameters to assess the progressive loss of collagen and proteoglycans, mimicking an osteoarthritis condition in ex-vivo bovine cartilage samples. Most ana...
These studies aimed to study the mechanisms of glaucomatous peripapillary scleral (PPS) remodeling by investigating IOP-induced changes in fibroblast actin-collagen alignment and nuclear morphology in mouse PPS. Cryosections from the optic nerve head...
Advances in virtual staining and spatial omics have revolutionized our ability to explore cellular architecture and molecular composition with unprecedented detail. Virtual staining techniques, which rely on computational algorithms to map molecular ...
Biochemical changes in the cervix during labor are not well understood. This gap in knowledge is significant, as understanding the precise biochemical processes can provide critical insights into the mechanisms of labor and potentially inform better ...
ACS biomaterials science & engineering
Mar 19, 2025
Effective drug development for bone-related diseases, such as osteoporosis and metastasis, is hindered by the lack of physiologically relevant in vitro models. Traditional platforms, including standard tissue culture plastic, fail to replicate the st...
Laboratory investigation; a journal of technical methods and pathology
Dec 13, 2024
Interstitial lung disease (ILD), characterized by inflammation and fibrosis, often suffers from low diagnostic accuracy and consistency. Traditional hematoxylin and eosin (H&E) staining primarily reveals cellular inflammation with limited detail on f...
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