Effect and safety of diluted vasopressin injection on bleeding during robot-assisted laparoscopic myomectomy: a protocol for a randomised controlled pilot trial.

Journal: BMJ open
PMID: 36115677

Abstract

INTRODUCTION: Even though the injection of diluted vasopressin into the uterus is expected to reduce intraoperative bleeding with decreased adverse effects during robot-assisted laparoscopic myomectomy (RALM), there is a lack of relevant trials to show its effect and safety. Thus, this study was designed to compare the effect and safety of vasopressin injection on bleedings based on dilution levels of vasopressin with constant volumes during RALM.

Authors

  • Eun Ji Lee
    Department of Pathology, Green Cross Laboratories, Yongin, Gyeonggi, South Korea.
  • Soo Jin Park
    Department of Obstetrcis and Gynecology, Seoul National University Hospital, Seoul, Korea (the Republic of).
  • Yup Kim
    Department of Obstetrcis and Gynecology, Seoul National University Hospital, Seoul, Korea (the Republic of).
  • Hyunji Lim
    Department of Obstetrcis and Gynecology, Seoul National University Hospital, Seoul, Korea (the Republic of).
  • Seungmee Lee
    Department of Obstetrics and Gynecology, Keimyung University School of Medicine, Daegu, Korea (the Republic of).
  • Ga Won Yim
    Department of Obstetrics and Gynecology, Institute of Women's Medical Life Science, Yonsei University College of Medicine, Seoul, Korea.
  • Gwonhwa Song
    Institute of Animal Molecular Biotechnology and Department of Biotechnology, Korea University, Seoul, Korea (the Republic of).
  • Hee Seung Kim
    Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea (the Republic of) bboddi0311@snu.ac.kr.

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