A Deep Learning-Based Generalized Empirical Flow Model of Glottal Flow During Normal Phonation.

Journal: Journal of biomechanical engineering
PMID:

Abstract

This paper proposes a deep learning-based generalized empirical flow model (EFM) that can provide a fast and accurate prediction of the glottal flow during normal phonation. The approach is based on the assumption that the vibration of the vocal folds can be represented by a universal kinematics equation (UKE), which is used to generate a glottal shape library. For each shape in the library, the ground truth values of the flow rate and pressure distribution are obtained from the high-fidelity Navier-Stokes (N-S) solution. A fully connected deep neural network (DNN) is then trained to build the empirical mapping between the shapes and the flow rate and pressure distributions. The obtained DNN-based EFM is coupled with a finite element method (FEM)-based solid dynamics solver for fluid-structure-interaction (FSI) simulation of phonation. The EFM is evaluated by comparing the N-S solutions in both static glottal shapes and FSI simulations. The results demonstrate a good prediction performance in accuracy and efficiency.

Authors

  • Yang Zhang
    Innovative Institute of Chinese Medicine and Pharmacy, Academy for Interdiscipline, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
  • Weili Jiang
    College of New Energy and Materials, China University of Petroleum-Beijing Beijing 102249 China zhouguanglin2@163.com.
  • Luning Sun
    Research Division of Clinical Pharmacology, First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210009, China. Electronic address: sunluning0521@aliyun.com.
  • Jianxun Wang
    Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556.
  • Xudong Zheng
    Department of Mechanical Engineering, University of Maine, Room 213 A, Boardman Hall, Orono, ME 04473.
  • Qian Xue
    Department of Mechanical Engineering, University of Maine, Room 213, Boardman Hall, Orono, ME 04473.