A plan verification platform for online adaptive proton therapy using deep learning-based Monte-Carlo denoising.

Journal: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Published Date:

Abstract

BACKGROUND PURPOSE: This study focused on developing a fast Monte Carlo (MC) plan verification platform via a deep learning (DL)-based denoising approach. It can maintain the MC dose calculation accuracy while significantly reducing the computation time. We also investigated its potential applications for online adaptive proton therapy (APT).

Authors

  • Guoliang Zhang
    Department of Digestion and Endoscopy, Tianjin First Central Hospital, Tianjin, China.
  • Xinyuan Chen
    National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
  • Jianrong Dai
    National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Kuo Men
    State Key Laboratory of Advanced Materials for Smart Sensing, GRINM Group Co., Ltd., Beijing 100088, China.